Dadalafilo 10 mg非标准药品名，相近为达拉非片

tadalafil 10 mg is a medication, mainly used for the treatment of erectile dysfunction (ED) in men and also for the treatment of symptoms of benign prostatic hyperplasia (BPH) in some cases.

1. Mechanism of action for erectile dysfunction

- Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor. In the normal process of penile erection, sexual stimulation causes the release of nitric oxide (NO) in the penile corpus cavernosum. NO activates guanylate cyclase, which increases the production of cyclic guanosine monophosphate (cGMP). cGMP relaxes the smooth muscles in the penile blood vessels, allowing increased blood flow into the penis, resulting in an erection. PDE5 breaks down cGMP. By inhibiting PDE5, tadalafil helps to maintain higher levels of cGMP, thus promoting and sustaining penile erection in response to sexual stimulation.

2. Use in benign prostatic hyperplasia

- In BPH, tadalafil helps to relax the smooth muscle in the prostate and bladder neck, which can improve urinary flow rate and relieve some of the obstructive symptoms associated with BPH, such as difficulty in starting urination, weak urine stream, and frequent urination.

3. Administration and precautions

- It is typically taken orally, usually as needed for erectile dysfunction (about 30 minutes to 1 hour before sexual activity, although it can be effective for up to 36 hours in some cases). For the treatment of BPH, it may be taken regularly once a day.

- Precautions include:

- It should not be used in combination with nitrates (such as nitroglycerin) as this can cause a dangerous drop in blood pressure.

- People with certain heart conditions, especially those taking medications for heart problems, should consult their doctor before using tadalafil.

- Side effects may include headache, flushing, indigestion, back pain, muscle aches, and nasal congestion.

达拉非片是一种用于治疗勃起功能障碍的药物，其主要成分是他达拉非，这种药物通过放松阴茎血管的平滑肌来改善血液流入，从而帮助男性在性刺激下获得和维持勃起。

在使用达拉非片时，您需要注意以下几点：

1、服用时间：通常建议在性生活前30分钟至1小时内服用，效果可以持续长达36小时。

2、剂量调整：初始推荐剂量为10mg，如果效果不佳或副作用过大，医生可能会调整剂量。

3、禁忌：如果您有心血管疾病、低血压、严重肝病或肾病等健康问题，应避免使用此药。

4、药物相互作用：请告知医生您正在使用的所有药物，包括处方药和非处方药，以避免潜在的药物相互作用。

5、副作用：常见的副作用包括头痛、消化不良、背痛和肌肉疼痛等，如果出现严重的副作用，如视力模糊或听力下降，请立即停药并咨询医生。

在使用任何药物之前，请务必咨询医生或药师，确保药物适合您的健康状况，并按照医嘱正确使用。