What is Cialis? An to Cialis.
Cialis is a medicine that is used primarily to treat erectile dysfunction (ED) in men.
1. Mechanism of action
-contains the active substance tadalafil. This substance acts by inhibiting the enzyme phosphodiesterase-5 (PDE-5). PDE-5 is responsible for the degradation of an important chemical messenger in male sexual response called cyclic monophosphate guanosin (cGMP). By inhibiting PDE-5, Cialis allows cGMP levels to remain elevated, resulting in relaxation of penis muscles and increased blood flow to this organ, facilitating erection.
2. Advantages and characteristics
-it has a relatively long duration of action. Compared to other ED medications, Cialis can act for a longer period of time, sometimes referred to as its "window effect" of up to 36 hours. This provides greater flexibility in terms of anticipation and planning of sexual activity compared to medications with shorter duration of action.
-it has also been investigated and used in some cases for the treatment of other prostate related urinary problems, such as benign prostate hyperplasia (BPH), as it can help relax the muscles of the lower urinary tract and improve associated urinary symptoms.
3. Precautions and contraindications
-it should not be used by men who take nitrates (e.g. nitroglycerin), as the combination can cause a drastic drop in blood pressure and put health at risk.
-it may have side effects, including headaches, heartburn, back pain, muscle pain, and redness of the skin (erythema), among others.
-it should be prescribed by a doctor, who should evaluate the general health of the patient, including his medical history and the medicines he is already taking, before recommending Cialis.